InteracDome

InteracDome is a resource consisting of inferred interaction sites in 4,000+ protein domains

InteracDome is a resource consisting of inferred interaction sites in 4,128 protein domains from Pfam (v31.0). InteracDome models domain interactions with DNA, RNA, small molecules, peptides and ions.

S.N. Kobren and M. Singh (2018) "Systematic domain-based aggregation of protein structures highlights DNA-, RNA-, and other ligand-binding positions." Nucleic Acids Res, 47(2): 582-593. [doi: 10.1093/nar/gky1224]

View Per-Position Binding Frequencies

In this interactive web browser, we only display per-domain-position binding frequencies

from the representable-NR set (see Download page for description)
that model interactions with DNA base, DNA backbone, RNA base, RNA backbone, peptides, and the 'ion', 'metabolite', and 'small molecule' groups.

Domain (organized by Pfam identifier)